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Scientific
capacity
Description
and activities
of the
infrastructure:
The
strategic goal
of the NCBMP is
the
institutionalization
and development
of the
scientific
field
"Biophotonics,
bionanophotonics"
as a part of
the national
and European
scientific
infrastructure.
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Main
activities are
aimed at:
- Creating
conditions for
conducting
basic research
to acquire new
knowledge about
the optical,
biochemical and
functional
properties of
biological
matter;
scientific and
applied
research for
the creation of
medical
diagnostic and
therapeutic
methods and
research for
the development
of the
methodological
and
instrumental
basis of
medical
theranostics
and
personalization
of medical
practice;
- Development
of prototypes,
demonstrations,
pilot projects,
testing and
validation of
new or improved
products,
processes or
services in a
representative
environment for
the real
operating
conditions.
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The
main tasks of
NCBMP are:
- Research in
the field of
tissue optics
and
spectroscopy of
biological
objects for
development of
diagnostic and
analytical
methods, laser
micro- and
nano-treatment
of biological
tissues for
application in
medical
therapy. Micro
/
nanolithographic
structuring for
the development
of nanoscale
sensors.
- Investigation
of the
relationship
between changes
in the (epi)
genome and
(epi)
transcriptome
from embryonic
development to
adulthood with
changes in
immunity and
the development
of pathology in
humans (and
animals), in
order to
improve quality
of life.
- Research of
photoinduced
processes in
micro- and
nanoscale
layers and
structures,
development of
high-tech
materials,
methods and
technologies
for optical
applications,
creation of new
materials and
recording
systems with
application in
biophotonics
and sensors.
- Development
of methods for
early diagnosis
of tumor
diseases, as
well as for
monitoring the
effectiveness
of therapeutic
treatment.
Screening
technology for
diagnosis and
monitoring of a
wide range of
diseases;
electroporation,
electrofusion,
electrotransformation,
electrotransmission
of
macromolecules
across
membranes,
electrochemotherapy
of tumors.
- Development
of multimodal
nanoparticles
capable of
delivering and
subsequently
releasing drugs
into target
tissues.
Development of
new optically
active
materials, new
coatings with
improved
biocompatibility
and
biodegradability
and new
technologies
for targeting
drug agents to
tumor cells.
- Development
of new photonic
and
nano-technological
medical
approaches and
products for
improving
health and
longevity in
all areas of
Nanomedicine
identified in
ISIS:
nanodiagnostics,
nanopharmacology,
nanoregenerative
medicine,
nanotherapy,
nanosurgery.
- Development
of new laser
methods,
medical devices
and methods
such as
"optical
biopsy" and
development of
a new medical
field -
"photodynamic /
sonodynamic
medicine".
- Complex
development of
the
“Theranostic
nanomedicine”
approach, for
“delivering the
right medicine
for a specific
patient at the
right time in
the right place
in the body”,
especially in
the treatment
of cancer.
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Impact /
benefits:
The obtained
results will
have an impact
on: creation of
a new
generation of
biovalidating
models of tumor
and other
pathologies
that mimic
living human or
animal tissue
and allow
complex testing
of the effects
of various
physical /
chemical
factors based
on methods of
biological
impact at the
level of
genetic
material; its
functional
state, cell
physiology,
tissue
functions.
These results
will affect the
fields of
biomedicine,
pharmacy,
clinical
medicine, in
its most modern
areas -
theranostics,
photodynamic
medicine,
nanomedicine.
Potential users
are the
scientific
community, the
biopharmaceutical
industry,
clinical
practice,
related
sciences -
veterinary
medicine,
biology,
chemistry.
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